MonoSodium Glutamate (MSG)
MSG, or Monosodium Glutamate is a salt of the amino acid. Multiple Amino acids are used by DNA to create a protein.
What happens when you digest MSG
- MSG is eaten.
- Cells in the hypothalamus that produce dopamine and regulate appetite are destroyed. The hypothalamus is an area of the brain that produces hormones that control, body temperature, hunger, moods, release of hormones from many glands, sex drive, sleep and thirst. Dopamine is a neurotransmitter that helps control the brain’s reward and pleasure centers. Dopamine also helps regulate movement and emotional responses, and it enables us not only to see rewards, but to take action to move toward them. Dopamine deficiency results in Parkinson’s Disease, and people with low dopamine activity may be more prone to addiction.
- Hypothalamus becomes leptin-resistant. Leptin (from the Greek leptos, meaning thin) is a protein hormone that helps to regulate body weight, metabolism and reproductive function. Hugely obese children with an inability to lose weight have been linked to an inability to produce leptin.
- Glutamate activates AMPK, which slows metabolism AND desire for physical activity (“lazy mice”). Glutamate is probably best known for it’s link to “monosodium glutamate” or “MSG. Glutamate is considered to be the major mediator of excitatory signals in the central nervous system and is involved in most aspects of normal brain function including cognition, memory and learning.
- The fat cells release leptin to stop AMPK, but the hypothalamus ignores the signal.
- Appetite stays high, activity is depressed. Calorie intake goes up, calories expended by metabolism go down, calories expended in activity go down.
- MSG although it is an amino acid, signals the pancreas to release insulin. Multiple Amino acids are used by DNA to create a protein. Insulin is provided within the body in a constant proportion to remove excess glucose from the blood, which otherwise would be toxic. When blood glucose levels fall below a certain level the body begins to use fat as an energy source. Glucose is a type of sugar the body uses for energy.
- Insulin drops our blood sugar – causing increased hunger at the same time it packs away excess calories as fat.
- Obesity. Diseases which may be caused by MSG are obesity, Type II diabetes, and high blood pressure.